2,5-Dichloropyrimidine
- Product Name
- 2,5-Dichloropyrimidine
- CAS No.
- 22536-67-0
- Chemical Name
- 2,5-Dichloropyrimidine
- Synonyms
- EOS-60492;2,5-Dichlo;2,5-chloropyrimidine;2,5-DICHLOROPYRIMIDINE;Macitentan Impurity 32;2,5‐Dichloropyridimidine;2,5-Dichloro-1,3-diazine;Pyrimidine, 2,5-dichloro-;2,5-Dichloropyrimidine>2,5-Dichloropyrimidine 97%
- CBNumber
- CB7750461
- Molecular Formula
- C4H2Cl2N2
- Formula Weight
- 148.98
- MOL File
- 22536-67-0.mol
2,5-Dichloropyrimidine Property
- Melting point:
- 48-55 °C
- Boiling point:
- 190°C
- Density
- 1.493
- Flash point:
- 140°C
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- -2.84±0.22(Predicted)
- form
- Powder
- color
- Off-white
- Water Solubility
- Slightly soluble in water.
- λmax
- 268nm(EtOH)(lit.)
- InChI
- InChI=1S/C4H2Cl2N2/c5-3-1-7-4(6)8-2-3/h1-2H
- InChIKey
- CEJAHXLRNZJPQH-UHFFFAOYSA-N
- SMILES
- C1(Cl)=NC=C(Cl)C=N1
- CAS DataBase Reference
- 22536-67-0(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H318Causes serious eye damage
H400Very toxic to aquatic life
- Precautionary statements
-
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- 720917
- Product name
- 2,5-Dichloropyrimidine
- Purity
- 97%
- Packaging
- 1g
- Price
- $10.4
- Updated
- 2024/03/01
- Product number
- D4045
- Product name
- 2,5-Dichloropyrimidine
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $37
- Updated
- 2024/03/01
- Product number
- D4045
- Product name
- 2,5-Dichloropyrimidine
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $148
- Updated
- 2024/03/01
- Product number
- H64066
- Product name
- 2,5-Dichloropyrimidine, 95%
- Packaging
- 5g
- Price
- $32.65
- Updated
- 2024/03/01
- Product number
- H64066
- Product name
- 2,5-Dichloropyrimidine, 95%
- Packaging
- 25g
- Price
- $127.65
- Updated
- 2024/03/01
2,5-Dichloropyrimidine Chemical Properties,Usage,Production
Uses
2,5-Dichloropyrimidine acid is employed as a important raw material and intermediate used in organic synthesis agrochemical, pharmaceutical and dyestuff field.
Preparation
2,5-Dichloropyrimidine was synthesised from 2-hydroxypyrimidine hydrochloride by treatment with aqueous chlorine solution. Reaction of the product with phosphoryl chloride in the presence of N,N-dimethylaniline gave the desired product in 40% yield. The sample was then purified by sublimation.
storage
Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.
structure and hydrogen bonding
C4H2Cl2N2, M=148.98 monoclinic, space group P21/m with a=6.077(3), b=19.771(8), c=7.399(3) ?, β=101.23(6)°, U=872 ?3 [from 2θ values of 29 reflections measured at±ω, 25 ≤2θ ≤ 38°, λ = 0.710 73?, T=150.0 K], Dcalc=1.702 g cm-3, Z=6, μ =0.993 mm-1[1].
References
[1] Blake A, et al. Structure Analysis Restrained by ab Initio Calculations: The Molecular Structure of 2,5-Dichloropyrimidine in Gaseous and Crystalline Phases. The Journal of Physical Chemistry, 1996; 100: 12280–12287.
2,5-Dichloropyrimidine Preparation Products And Raw materials
Raw materials
Preparation Products
2,5-Dichloropyrimidine Suppliers
View Lastest Price from 2,5-Dichloropyrimidine manufacturers
- Product
- 2,5-Dichloropyrimidine 22536-67-0
- Price
- US $1250.00/Kg
- Min. Order
- 1Kg
- Purity
- 98
- Supply Ability
- 500 Kg
- Release date
- 2024-04-26
- Product
- 2,5-Dichloropyrimidine 22536-67-0
- Price
- US $36.00-1.10/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-08
- Product
- 2,5-Dichloropyrimidine 22536-67-0
- Price
- US $30.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100 tons
- Release date
- 2022-10-17